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DMT-2'-O-TBDMS-C(Ac)-CE Phosphoramidite Cap Analogs a 2’-O-tert-butyldimethylsilyl (TBDMS) protecting group

SKU: 47252262486

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Description

a 2’-O-tert-butyldimethylsilyl (TBDMS) protecting group for 2’-hydroxyl protection

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It can resist degradation by nucleases

pseudouridine can reduce innate immune recognition compared with unmodified uridine and improve RNA stability and translational performance

its unique covalently closed circular RNA structure can prevent RNA from being degraded by nucleases

DMT-2'-O-TBDMS-C(Ac)-CE Phosphoramidite Cap Analogs a 2’-O-tert-butyldimethylsilyl (TBDMS) protecting groupDMT 2' O TBDMS C(Ac) CE Phosphoramidite is a protected ribonucleoside building block used for solid phase RNA oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a 2' O tert butyldimethylsilyl (TBDMS) protecting group for 2' hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a acetyl (Ac) base protecting group on cytosine. TBDMS offers excellent stability for protecting

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